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Incyte Had These Key Collaborations and Developments in 2Q17

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Incyte’s Jakafi and its collaborations

Incyte (INCY) distributes its key drug, Jakafi, through its own network of specialty pharmacy providers and wholesalers in US markets. The company has a well-established distribution network for US markets.

But for outside of US markets, Incyte has entered into a collaborative agreement with Novartis (NVS) for the development and commercialization of Jakafi. Novartis sells Jakafi as Jakavi, and Incyte receives royalties on the total sales of Jakavi from Novartis.

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Recent developments

The recent developments for Incyte include the following:

  • On July 25, 2017, Eli Lilly (LLY) and Incyte announced that the resubmission of a NDA (new drug application) to the FDA (US Food and Drug Administration) is expected to be delayed beyond 2017. The resubmission will take at least 18 months
  • On July 20, 2017, Incyte announced the first patient to be treated with Itacitinib under its Gravitas-301 phase-III study, which evaluates the efficacy and safety of Itacitinib as a first-line treatment for acute graft-versus-host disease.
  • On July 3, 2017, the Japanese Ministry of Health, Labor, and Welfare granted marketing approval for Olumiant 2 mg and 4 mg tablets in Japan for the treatment of patients with rheumatoid arthritis.
  • On June 16, 2017, Eli Lilly and Incyte announced a pooled analysis of data from eight Olumiant clinical trials. The data showed that patients treated with baricitinib and patients treated with a placebo reported similar rates of serious infections in moderate-to-severe rheumatoid arthritis.
  • On June 5, 2017, Incyte released the data from an ongoing phase-1/2 Echo-204 clinical trial, which evaluates the drug Epacadostat in combination with Bristol-Myers Squibb’s (BMY) Opdivo (nivolumab) in multiple advanced solid tumors.
  • On June 5, 2017, Incyte also updated data from its ongoing phase-1/2 Echo-202 clinical trial, which evaluates epacadostat in combination with Merck’s (MRK) Keytruda (pembrolizumab) in multiple tumor types.

To divest company-specific risks, investors can consider ETFs like the iShares US Healthcare ETF (IYH), which has 0.7% of its total assets in Incyte (INCY). IYH also has 3.0% in Bristol-Myers Squibb (BMY), 5.5% in Merck (MRK), and 2.5% in Eli Lilly (LLY).

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