The CVMD segment
AstraZeneca’s (AZN) CVMD (Cardiovascular and Metabolic Disease) segment is the company’s largest contributor to total revenues. The CVMD segment contributed nearly 32.4% of total revenues in 3Q16, following a strong performance of Onglyza, Brilinta, Bydureon, Farxiga, Byetta, Crestor, and Seloken. These revenues were partially offset by lower sales of Alakand and other products.
Brilinta-Brilique, a growth platform product, is used to prevent unwanted blood clots in heart and blood vessels. The FDA (US Food and Drugs Administration) approved a new 60 mg dose for Brilinta in the second half of 2015.
The drug’s 3Q16 revenues reported an operational rise of 22% to $208 million, with a 22% rise in US sales at $84 million, an ~11% rise in European market sales, and a ~60% rise in sales in emerging markets at constant exchange rates.
Onglyza, a diabetes product that controls blood sugar level, reported a 16% fall in revenues at constant exchange rates, driven by a 17% fall in sales in US markets, a 21% fall in sales in emerging markets, and a 22% fall in European markets.
Crestor, which is used to reduce the cholesterol and triglycerides in the blood, contributed ~12.1% of total 3Q16 revenues for AstraZeneca. At constant exchange rates, Crestor revenues fell 44% at $688 million in 3Q16.
In US markets, Crestor’s revenues fell 82% to $124 million due to patent expiry in May 2016. European markets reported flat revenues of $219 million due to competition from generic statins, while sales in emerging markets rose 17% at constant exchange rates in 3Q16.
Other CVMD products
Other products in this segment include Farxiga-Forxiga, Bydureon, Byetta, and Seloken. Farxiga-Forxiga’s 3Q16 revenues grew 64% due to higher demand in all markets including the US, Europe, and emerging markets. Bydureon revenues fell 10%, while Byetta sales fell 15% in 3Q16. The company is making constant efforts to expand its presence in diabetes products in Europe with the help of Bydureon.
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