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How Novartis’s Tasigna Is Looking Now

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Nov. 16 2017, Updated 9:00 a.m. ET

Tasigna revenue trends

In 3Q17, Novartis’s (NVS) Tasigna reported revenues of $482 million, which was ~9% higher YoY (year-over-year) and 4% higher QoQ (quarter-over-quarter). Sales growth in the US and emerging markets primarily attributed to the revenue growth of Novartis in 3Q17.

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ENTESTfreedom and ENTESTop trials

In June 2017, Novartis presented the results from the additional analysis of its phase-3 ENESTfreedom and ENESTop trials. The phase-3 ENESTfreedom and ENESTop trial demonstrated that around half of adult individuals with Philadelphia chromosome-positive chronic myeloid leukemia (or CML) in the chronic phase who discontinued Tasigna remained in treatment-free remission (or TFR) for approximately two years after stopping therapy.

The ENTESTfreedom trial evaluated the potential of discontinuation of Tasigna therapy in eligible candidates with Philadelphia chromosome-positive chronic myeloid leukemia (or CML) who achieved a sustained deep molecular response (or DMR) after a minimum of three years of first-line Tasigna therapy.

In the marketplace, Novartis Tasigna competes with Bristol-Myers Squibb’s (BMY) Sprycel, Pfizer’s (PFE) Bosulif, and Takeda Pharmaceuticals’ (TKPYY) Iclusig. In 3Q17, Sprycel reported revenues of ~$509 million. The Vanguard International High Dividend Yield ETF (VYMI) has ~1.18% of its total portfolio holdings in NVS.

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