X
<

Should Investors Be Interested in Merck in Fiscal 2016?

PART:
1 2 3 4 5 6 7 8
Part 6
Should Investors Be Interested in Merck in Fiscal 2016? PART 6 OF 8

Merck’s Zetia and Vytorin: More Generic Competition in 2017

Zetia and Vytorin patent expiry

The US patents of Merck’s (MRK) cardiovascular drugs, Zetia and Vytorin, expire in April 2017. In May 2010, Merck and Glenmark Pharmaceuticals entered into an agreement that allowed the latter to launch a generic version of Zetia on December 12, 2016, or even earlier. Accordingly, Glenmark Pharmaceuticals launched the first generic version of Zetia in the US market. As generic competition continues to rise, Merck expects a steep fall in Zetia’s revenues in the future.

According to MedicineNet.com, “Vytorin is a combination of ezetimibe (Zetia) and simvastatin (Zocor) that is used for treating high levels of cholesterol in the blood.” As a result, Vytorin is expected to go off-patent with Zetia in April 2017.

Loss of Zetia and Vytorin’s revenues might have a negative impact on Merck’s share prices as well as the Vanguard Total Stock Market ETF (VTI). Merck account for ~0.71% of VTI’s total portfolio holdings.

Merck’s Zetia and Vytorin: More Generic Competition in 2017

The above chart shows the falling revenue trend for Zetia and Vytorin since 2013. In addition to generic competition, Zetia and Vytorin also compete with statins such as Pfizer’s (PFE) Lipitor, Astrazeneca’s (AZN) Crestor, and Novartis’ (NVS) Lescol.

International markets

In international markets, Zetia and Vytorin are marketed as Ezetrol and Inegy, respectively. Ezetrol is expected to lose its patent protection in most European markets by April 2018. Inegy might lose patent exclusivity in April 2019.

Adempas revenues

Based on a collaboration agreement entered in October 2014, Bayer AG holds commercial rights for a pulmonary arterial hypertension drug, Adempas, in the US. Merck has rights to the drug in international markets. Merck commenced marketing Adempas in European markets in 2016. In the first nine months of 2016, Merck recorded $120 million revenues attributed to Adempas.

In the next part, we’ll analyze growth prospects for Merck’s general medicine and women’s health portfolio.

Interested in AZN? Receive notifications on the latest research and sign up for a Market Realist account in one simple step:

Suceess! Your Market Realist account has been created and you’ll receive email alerts on the latest research. Check your email for your temporary account password.

Success! has been added to your Ticker Alerts.

Success! has been added to your Ticker Alerts. Click here to manage subscriptions.

X

Please select a profession that best describes you: